Start Christian McCaffrey or George Holani? Week 6

Our Week 6 call

Start Christian McCaffrey over George Holani in Week 6.

Market-based projections have Christian McCaffrey at 21.7 points and George Holani at 5.3, a gap of 16.4.

What the market projects

Player markets imply 21.7 fantasy points for Christian McCaffrey, with 100 percent of the markets a RB needs posted.

The market has Christian McCaffrey at 58.5 rushing yards, 39.5 receiving yards and 4.5 receptions, with a 71% chance to score a touchdown (10, 10, 8 and 10 market sources).

Player markets imply 5.3 fantasy points for George Holani, with 100 percent of the markets a RB needs posted.

The market has George Holani at 14.5 rushing yards, 9.5 receiving yards and 1.5 receptions, with a 20% chance to score a touchdown (12, 13, 13 and 13 market sources).

That puts Christian McCaffrey 16.4 points ahead of George Holani on the market projections.

Injury status

Christian McCaffrey is not on the injury report.

George Holani is not on the injury report.

Usage before Week 6

Through Week 5, Christian McCaffrey played 69 percent of SF snaps, took 46 percent of the carries, drew 18 percent of the targets and had 34 percent of the red zone chances.

Christian McCaffrey, Week 2 against MIA: 27 of 52 snaps, 10 carries for 23 yards, 4 targets and 4 catches for 43 yards, 2 touchdowns.

Christian McCaffrey, Week 3 against ARI: 45 of 54 snaps, 15 carries for 75 yards, 5 targets and 4 catches for 41 yards, 1 touchdown.

Christian McCaffrey, Week 4 against DEN: 49 of 66 snaps, 15 carries for 52 yards, 5 targets and 3 catches for 18 yards, 1 touchdown.

Christian McCaffrey, Week 5 against SEA: 49 of 60 snaps, 11 carries for 68 yards, 3 targets and 3 catches for 15 yards, 1 touchdown.

Through Week 5, George Holani played 36 percent of SEA snaps, took 19 percent of the carries, drew 8 percent of the targets and had 13 percent of the red zone chances.

George Holani, Week 2 against ARI: 18 of 70 snaps, 4 carries for 13 yards, 1 target and 1 catch for 2 yards.

George Holani, Week 3 against WAS: 24 of 67 snaps, 3 carries for 10 yards, 5 targets and 5 catches for 48 yards.

George Holani, Week 4 against LAC: 22 of 60 snaps, 7 carries for 18 yards, 1 target and 1 catch for 2 yards.

George Holani, Week 5 against SF: 26 of 63 snaps, 4 carries for 7 yards, 4 targets and 4 catches for 24 yards.

Their 2025 seasons

In 2025, Christian McCaffrey played 17 games for SF and scored 416.6 PPR points, 24.5 a game, finishing RB1.

He ran 311 times for 1202 yards and 10 touchdowns, and caught 102 of 129 targets for 924 yards.

He was on the field for 83 percent of the offense's snaps in the games he played.

In 2025, George Holani played 11 games for SEA and scored 20.8 PPR points, 1.9 a game, finishing RB93.

He ran 22 times for 73 yards and 1 touchdown, and caught 2 of 2 targets for 15 yards.

He was on the field for 5 percent of the offense's snaps in the games he played.

Their other Week 6 calls

• Start Christian McCaffrey over Bhayshul Tuten.
• Start Bijan Robinson over Christian McCaffrey.
• Start Christian McCaffrey over Cam Skattebo.
• Start Bhayshul Tuten over George Holani.
• Start Cam Skattebo over George Holani.
• Start George Holani over Chris Rodriguez Jr..