Start Bo Nix or Brock Purdy? Week 2

Our Week 2 call

Start Brock Purdy over Bo Nix in Week 2.

De-vigged player props project Brock Purdy at 21.3 points and Bo Nix at 18.5, a gap of 2.8. Both numbers are scaled up from a partial market: the books have not posted every stat the position needs, so the rest is estimated from what they have. Drafters take Brock Purdy at ADP 88 and Bo Nix at 108.

What the books imply

Player prop markets imply 21.3 fantasy points for Brock Purdy, with 100 percent of the markets a QB needs posted.

Player prop markets imply 18.5 fantasy points for Bo Nix, with 100 percent of the markets a QB needs posted.

That puts Brock Purdy 2.8 points ahead of Bo Nix on the books.

Week 2 matchups

Brock Purdy and SF host MIA on Sunday at 4:25 PM ET.

MIA allowed 15.8 fantasy points to QBs in its one game this season, the 15th fewest in the league.

Quarterbacks threw for 160 yards and 3 touchdowns against MIA, with 2 interceptions.

Bo Nix and DEN host JAX on Sunday at 4:05 PM ET.

JAX allowed 15.0 fantasy points to QBs in its one game this season, the 12th fewest in the league.

Quarterbacks threw for 205 yards and a touchdown against JAX, with an interception.

By points allowed to the position, Brock Purdy has the softer matchup.

Injury status

Brock Purdy is not on the injury report.

Bo Nix is not on the injury report.

Usage before Week 2

Through Week 1, Brock Purdy played 100 percent of SF snaps, dropped back 36 times and threw an average of 4.4 air yards per attempt.

Brock Purdy, Week 1 against LAR: 65 of 65 snaps, 25 of 34 passes for 205 yards, 3 touchdowns and 1 interception, 5 carries for 29 yards.

Through Week 1, Bo Nix played 100 percent of DEN snaps, dropped back 33 times and threw an average of 3.3 air yards per attempt.

Bo Nix, Week 1 against KC: 51 of 51 snaps, 17 of 28 passes for 131 yards, 1 touchdown and 1 interception, 2 carries for 3 yards.

Their 2025 seasons

In 2025, Brock Purdy played 9 games for SF and scored 187.4 PPR points, 20.8 a game, finishing QB24.

He completed 197 of 284 passes for 2167 yards, 20 touchdowns and 10 interceptions, and ran 33 times for 147 yards and 3 touchdowns.

He was on the field for 98 percent of the offense's snaps in the games he played.

Brock Purdy, Week 18 of 2025 against SEA: 42 of 42 snaps, 19 of 27 passes for 127 yards, 0 touchdowns and 1 interception, 2 carries for 21 yards, 6.2 PPR points.

Brock Purdy, Week 17 of 2025 against CHI: 72 of 72 snaps, 24 of 33 passes for 303 yards, 3 touchdowns and 1 interception, 6 carries for 28 yards, 37.9 PPR points.

In 2025, Bo Nix played 17 games for DEN and scored 315.8 PPR points, 18.6 a game, finishing QB7.

He completed 388 of 612 passes for 3931 yards, 25 touchdowns and 11 interceptions, and ran 83 times for 356 yards and 5 touchdowns.

He was on the field for 100 percent of the offense's snaps in the games he played.

Bo Nix, Week 18 of 2025 against LAC: 14 of 23 passes for 141 yards, 0 touchdowns and 0 interceptions, 8 carries for 49 yards, 10.5 PPR points.

Bo Nix, Week 17 of 2025 against KC: 72 of 72 snaps, 26 of 38 passes for 182 yards, 1 touchdown and 1 interception, 9 carries for 42 yards, 20.5 PPR points.

Their other Week 2 calls

• Start Brock Purdy over Caleb Williams.
• Start Jalen Hurts over Brock Purdy.
• Start Brock Purdy over Jared Goff.
• Start Bo Nix over Baker Mayfield.
• Start Bo Nix over Jared Goff.
• Start Jaxson Dart over Bo Nix.