Start Bo Nix or Patrick Mahomes? Week 2

Our Week 2 call

Start Bo Nix over Patrick Mahomes in Week 2.

De-vigged player props project Bo Nix at 18.5 points and Patrick Mahomes at 16.0, a gap of 2.5. Both numbers are scaled up from a partial market: the books have not posted every stat the position needs, so the rest is estimated from what they have. Drafters take Bo Nix at ADP 108 and Patrick Mahomes at 111.

What the books imply

Player prop markets imply 18.5 fantasy points for Bo Nix, with 100 percent of the markets a QB needs posted.

Player prop markets imply 16.0 fantasy points for Patrick Mahomes, with 100 percent of the markets a QB needs posted.

That puts Bo Nix 2.5 points ahead of Patrick Mahomes on the books.

Week 2 matchups

Bo Nix and DEN host JAX on Sunday at 4:05 PM ET.

JAX allowed 15.0 fantasy points to QBs in its one game this season, the 12th fewest in the league.

Quarterbacks threw for 205 yards and a touchdown against JAX, with an interception.

Patrick Mahomes and KC host IND on Sunday at 8:20 PM ET.

IND allowed 25.0 fantasy points to QBs in its one game this season, the 7th most in the league.

Quarterbacks threw for 324 yards and a touchdown against IND, with no interceptions.

By points allowed to the position, Patrick Mahomes has the softer matchup.

Injury status

Bo Nix is not on the injury report.

Patrick Mahomes is not on the injury report.

Usage before Week 2

Through Week 1, Bo Nix played 100 percent of DEN snaps, dropped back 33 times and threw an average of 3.3 air yards per attempt.

Bo Nix, Week 1 against KC: 51 of 51 snaps, 17 of 28 passes for 131 yards, 1 touchdown and 1 interception, 2 carries for 3 yards.

Through Week 1, Patrick Mahomes played 100 percent of KC snaps, dropped back 33 times and threw an average of 4.9 air yards per attempt.

Patrick Mahomes, Week 1 against DEN: 69 of 69 snaps, 15 of 27 passes for 184 yards, 2 touchdowns and 1 interception, 4 carries for 27 yards.

Their 2025 seasons

In 2025, Bo Nix played 17 games for DEN and scored 315.8 PPR points, 18.6 a game, finishing QB7.

He completed 388 of 612 passes for 3931 yards, 25 touchdowns and 11 interceptions, and ran 83 times for 356 yards and 5 touchdowns.

He was on the field for 100 percent of the offense's snaps in the games he played.

Bo Nix, Week 18 of 2025 against LAC: 14 of 23 passes for 141 yards, 0 touchdowns and 0 interceptions, 8 carries for 49 yards, 10.5 PPR points.

Bo Nix, Week 17 of 2025 against KC: 72 of 72 snaps, 26 of 38 passes for 182 yards, 1 touchdown and 1 interception, 9 carries for 42 yards, 20.5 PPR points.

In 2025, Patrick Mahomes played 14 games for KC and scored 296.7 PPR points, 21.2 a game, finishing QB11.

He completed 315 of 502 passes for 3587 yards, 22 touchdowns and 11 interceptions, and ran 64 times for 422 yards and 5 touchdowns.

He was on the field for 97 percent of the offense's snaps in the games he played.

Patrick Mahomes, Week 15 of 2025 against LAC: 56 of 61 snaps, 16 of 28 passes for 189 yards, 0 touchdowns and 1 interception, 2 carries for 15 yards, 14.1 PPR points.

Their other Week 2 calls

• Start Bo Nix over Baker Mayfield.
• Start Brock Purdy over Bo Nix.
• Start Bo Nix over Jared Goff.
• Start Baker Mayfield over Patrick Mahomes.
• Start Jared Goff over Patrick Mahomes.
• Start Jaxson Dart over Patrick Mahomes.