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49ers vs Cowboys prediction, Week 10

San Francisco 49ers at Dallas Cowboys, Sun, Nov 15, 4:25 PM ET on Fox. The 49ers project to win, 30 to 26, a margin of about 4 points over the Cowboys.

Projected score

49ers
30
Cowboys
26

Projected combined points: 56. Each team's score is the points the game's market implies for it, in whole points. Fantasy points use PPR scoring.

San Francisco 49ersProjected points: 30

Injuries that matter: Mike Evans (WR, Out), Deebo Samuel Sr. (WR, Out).

Dallas CowboysProjected points: 26

Injuries that matter: George Pickens (WR, Out), Jake Ferguson (TE, Out), Tyler Goodson (RB, Out).

Weather

Played under a roof: weather is not a factor. Every game's forecast

Other Week 10 predictions

By the Parlae deskProjections updated Nov 10, 2026 at 1:22 PM ETHow this is builtReport a wrong number